iimena

Integrating Informatics and Metabolic Engineering for the biosynthesis of Novel Antibiotics

Welcome to the homepage of the iimena project consortium

 

The iimena-project aims to integrate state-of-the art screening technologies, bioinformatics and metabolic engineering approches in order to identify and characterize novel secondary metabolites from actinomycetes, which can become lead-candidates for antibiotic drug development.

The iimena-project is funded by a Challenge Grant of the:

<b>iimena</b><br/><br/>Integrating Informatics and Metabolic Engineering for the biosynthesis of Novel Antibiotics

The iimena project

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NEW AND HIGHLY COMPLEX ANTIBACTERIAL MACROLIDES FROM AMYCOLATOPSIS SP.
December 9, 2021
As a result of the IIMENA project, we now report the discovery of gargantulides B and C, which are among the largest and most complex bacterial polyketides discovered so far. These huge mac...
New CRISPR-prime editing toolkit to engineer E. coli
September 3, 2021
Scientists from DTU Biosustain and KAIST funded by Novo Nordisk Foundation and part of the iimena project have developed a new CRISPR-prime editing toolkit to engineer E. coli. Have a look a...
NEW METABOLITES PRODUCED FROM A RARE ACTINOMYCETE
August 24, 2021
As part of the iimena project, we are investigating the genomes, as well as the metabolite profiles of many actinomycete strains. Despite the well-known Streptomyces, there are other undere...