12Jul 2020 by Tilmann Weber

Streptomyces CRISPR Protocols published in Nature Protocols

News
An important aim of the iimena project is to develop methods that enable us to more efficiently get access to the potential new antibiotics produced by actinomycetes. One of the most important developments in the recent years have been molecular tools using CRISPR technologies. iimena scientists have been on the forefront of developing such tools and sharing them with the international research community. We are therefore very happy that a protocol now has been published in Nature Protocols. In the publication, titled "CRISPR–Cas9, CRISPRi and CRISPR-BEST-mediated genetic manipulation in streptomycetes", users of the toolkit find very detailed step-by-step guides on how to most efficiently use our toolkit. Link to the protocol:Tong, Y. et al. CRISPR-Cas9, CRISPRi and CRISPR-BEST-mediated genetic manipulation in streptomycetes. Nat. Protoc., doi:10.1038/s41596-020-0339-z (2020). Link to interactive PDF…
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11Sep 2018 by Tilmann Weber

Genome Mining Workshop 2018

News
We are looking forward to host the 3rd International Workshop for early career scientists on Genome Mining for Natural Products, which will take place from 12.-14. September at DTU Biosustain. 30 participants from 8 different countries will get two days of intensive training using the state of the art bioinformatics tools antiSMASH and NORINE and will have the opportunity to directly interact with the developers of the software.
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