Are you a highly motivated postdoctoral researcher with an interest in CRISPR applications in microorganisms, and experience in molecular biology with actinomycetes, and would like to join our highly international research center? PLEASE NOTE THAT THIS POSITION IS NOT PART OF THE IIMENA PROJECT.
The iimena project funded by a Challenge Grant by the Novo Nordisk Foundation integrates BGC discovery with innovative high throughput screening, adaptive laboratory evolution and metabolic engineering using newest technologies available, to tap into the secret world of active compounds produced by bacteria and fungi to reveal the next generation of antibiotics. Read the full article here .
An important aim of the iimena project is to develop methods that enable us to more efficiently get access to the potential new antibiotics produced by actinomycetes. One of the most important developments in the recent years have been molecular tools using CRISPR technologies. iimena scientists have been on the forefront of developing such tools and sharing them with the international research community. We are therefore very happy that a protocol now has been published in Nature Protocols. In the publication, titled "CRISPR–Cas9, CRISPRi and CRISPR-BEST-mediated genetic manipulation in streptomycetes", users of the toolkit find very detailed step-by-step guides on how to most efficiently use our toolkit. Link to the protocol:Tong, Y. et al. CRISPR-Cas9, CRISPRi and CRISPR-BEST-mediated genetic manipulation in streptomycetes. Nat. Protoc., doi:10.1038/s41596-020-0339-z (2020). Link to interactive PDF…
Today we had the iimena annual scientific project meeting, this time online due to the COVID-19 situation, with all the partners from the IIMENA project funded by a Challenge Grant of the Novo Nordisk Foundation. The meeting allowed the partners to present their latest update on the results from the project as well as the next steps and plans for the future. We had the pleasure to introduce 3 new DTU team members and each of them had a short presentation on their projects.